Clinical Studies and Case Reports

On this site you will find clinical studies with cannabis or single cannabinoids in different diseases and case reports on the use of cannabis by patients.
You may search for diseases (indications), authors, medication, study design (controlled study, open trial, case report etc.) and other criteria.

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TitleCannabis for restless legs syndrome: a report of six patients
Author(s)Megelin T., Ghorayeb I.
Journal, Volume, IssueSleep Medicine, 38, 182-183
Major outcome(s)Cannabis may be helpful in restless legs syndrome according to case reports

Restless legs syndrome (RLS) is a chronic and sometimes severe sensorimotor disorder of still unclear pathophysiology [1]. Usually symptoms respond well to dopamine agonists (DA), opiates, or anticonvulsants, used either alone or in combination. However, a subset of patients remains refractory to medical therapy, and serious side effects such as augmentation and impulse control disorder have been observed with DA. We present six patients' spontaneous reports of a remarkable and total remission of RLS symptoms following cannabis use.

Duration (days)
DesignUncontrolled case report
Type of publicationMedical journal
Address of author(s)
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