Clinical Studies and Case Reports

On this site you will find clinical studies with cannabis or single cannabinoids in different diseases and case reports on the use of cannabis by patients.
You may search for diseases (indications), authors, medication, study design (controlled study, open trial, case report etc.) and other criteria.

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TitleTherapeutic use of cannabis by crack addicts in Brazil.
Author(s)Labigalini E Jr, Rodrigues LR, Da Silveira DX.
Journal, Volume, IssueJ Psychoactive Drugs 1999;31(4):451-5.
Major outcome(s)Cannabis use helped patients to quit crack use by reducing the craving symptoms

This study ensued from clinical observations based on spontaneous accounts by crack abusers undergoing their first psychiatric assessment, where they reported using cannabis in an attempt to ease their own withdrawal symptoms. Throughout a period of nine months, the researchers followed up on 25 male patients aged 16 to 28 who were strongly addicted to crack, as diagnosed through the Composite International Diagnostic Interview (CIDI), according to CID-10 and DSM-IV diagnostic criteria. Most of the subjects (68%, or 17 individuals) ceased to use crack and reported that the use of cannabis had reduced their craving symptoms, and produced subjective and concrete changes in their behavior, helping them to overcome crack addiction. The authors discuss some psychological, pharmacological and cultural aspects of these findings.

Duration (days)
Participants25 patients dependent from crack
DesignOpen study
Type of publicationMedical journal
Address of author(s)Departamento De Psiquiatria, Escola Paulista De Medicina, Universidade Federal De São Paulo, Brazil.
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