Clinical Studies and Case Reports

On this site you will find clinical studies with cannabis or single cannabinoids in different diseases and case reports on the use of cannabis by patients.
You may search for diseases (indications), authors, medication, study design (controlled study, open trial, case report etc.) and other criteria.

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TitleSurvey of cannabis use in patients with amyotrophic lateral sclerosis.
Author(s)Amtmann D, Weydt P, Johnson KL, Jensen MP, Carter GT.
Journal, Volume, IssueAm J Hosp Palliat Care 2004;21(2):95-104
Major outcome(s)Moderate improvement of pain, spasticity, appetite and depression
IndicationAppetite loss/weight loss;Spasticity;Pain;DepressionAbstract

Cannabis (marijuana) has been proposed as treatment for a widening spectrum of medical conditions and has many properties that may be applicable to the management of amyotrophic lateral sclerosis (ALS). This study is the first, anonymous survey of persons with ALS regarding the use of cannabis. There were 131 respondents, 13 of whom reported using cannabis in the last 12 months. Although the small number of people with ALS that reported using cannabis limits the interpretation of the survey findings, the results indicate that cannabis may be moderately effective at reducing symptoms of appetite loss, depression, pain, spasticity, and drooling. Cannabis was reported ineffective in reducing difficulties with speech and swallowing, and sexual dysfunction. The longest relief was reported for depression (approximately two to three hours).

Duration (days)
Participants131 patients with amyotrophic lateral sclerosis
Type of publicationMedical journal
Address of author(s)Department of Rehabilitation Medicine, University of Washington School of Medicine, Seattle, Washington, USA.
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