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cannabinoids in different diseases and case reports on the use of cannabis by
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|Title||Analgesic effect of delta-9-tetrahydrocannabinol.|
|Author(s)||Noyes R Jr, Brunk SF, Baram DA, Canter A|
|Journal, Volume, Issue||Journal of Clinical Pharmacology 1975;15(2-3):139-143|
|Major outcome(s)||pain relief with 15-20 mg THC|
A preliminary trial of oral delta-9-tetrahydrocannabinol (THC) demonstrated an analgesic effect of the drug in patients experiencing cancer pain. Placebo and 5, 10, 15, and 20 mg THC were administered double blind to ten patients. Pain relief significantly superior to placebo was demonstrated at high dose levels (15 and 20 mg). At these levels, substantial sedation and mental clouding were reported.
|Participants||10 cancer patients|
|Type of publication|
|Address of author(s)|