Clinical Studies and Case Reports

On this site you will find clinical studies with cannabis or single cannabinoids in different diseases and case reports on the use of cannabis by patients.
You may search for diseases (indications), authors, medication, study design (controlled study, open trial, case report etc.) and other criteria.

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TitleInhalation marijuana as an antiemetic for cancer chemotherapy.
Author(s)Vinciguerra V, Moore T, Brennan E.
Journal, Volume, IssueNew York State Journal of Medicine 1988;88:525-527.
Major outcome(s)Marijuana effective as antiemetic agent
IndicationNausea/vomiting;Cancer;Cancer chemotherapyAbstract

A prospective pilot study of the use of inhalation marijuana as an antiemetic for cancer chemotherapy was conducted. Fifty-six patients who had no improvement with standard antiemetic agents were treated and 78% demonstrated a positive response to marijuana. Younger age and prior marijuana exposure were factors that predicted response to treatment. Toxicity was mild and consisted primarily of sedation and xerostomia. This preliminary trial suggests the usefulness of inhalation marijuana as an antiemetic agent. Because of the lack of a randomized placebo control group, the precise role of this agent is unclear. Further studies should include derivatives of this substance in combination with standard effective drugs to control chemotherapy-induced nausea and vomiting.

Duration (days)
Participants56 patients
DesignOpen study
Type of publicationMedical journal
Address of author(s)
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