Clinical Studies and Case Reports

On this site you will find clinical studies with cannabis or single cannabinoids in different diseases and case reports on the use of cannabis by patients.
You may search for diseases (indications), authors, medication, study design (controlled study, open trial, case report etc.) and other criteria.

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TitleDelta-9-tetrahydrocannabinol shows antispastic and analgesic effects in a single case double-blind trial.
Author(s)Maurer M, Henn V, Dittrich A, Hofmann A
Journal, Volume, IssueEur Arch Psychiatry Clin Neurosci 1990;240(1):1-4
Major outcome(s)THC and codeine reduced pain; THC reduced spasticity
IndicationSpasticity;Spinal cord injury;PainAbstract

A double-blind study was performed comparing 5 mg delta-9- tetrahydrocannabinol (THC) p.o., 50 mg codeine p.o., and placebo in a patient with spasticity and pain due to spinal cord injury. The three conditions were applied 18 times each in a randomized and balanced order. Delta-9-THC and codeine both had an analgesic effect in comparison with placebo. Only delta-9-THC showed a significant beneficial effect on spasticity. In the dosage of THC used no altered consciousness occurred.

Dose(s)5 mg per day
Duration (days)18
Participants1 patient with spinal cord injury
DesignControlled study
Type of publication
Address of author(s)
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