Clinical Studies and Case Reports

On this site you will find clinical studies with cannabis or single cannabinoids in different diseases and case reports on the use of cannabis by patients.
You may search for diseases (indications), authors, medication, study design (controlled study, open trial, case report etc.) and other criteria.




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TitleMarijuana smoking and reduced pressure in human eyes: drug action or epiphenomenon?
Author(s)Flom MC, Adams AJ, Jones RT
Journal, Volume, IssueInvest Ophthalmol. 1975 Jan;14(1):52-5.
Major outcome(s)IOP reduction in 7 of 15
IndicationGlaucomaAbstract
MedicationDelta-9-THC

Normal pressure within the human eye was reduced after smoking a socially relevant dose of marijuana (12 mg. delta9-9-tetrahydrocannabinol), but only for light to moderate users who experienced a substantial "high" and a state of peaceful relaxation from the experimental dose. Analysis suggests an indirect effect of the drug associated with relaxation-a psychophysiologic state that can be produced by drug and nondrug means.

Route(s)Inhalation
Dose(s)12 mg
Duration (days)
Participants15 healthy subjects
DesignOpen study
Type of publicationMedical journal
Address of author(s)
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