Clinical Studies and Case Reports

On this site you will find clinical studies with cannabis or single cannabinoids in different diseases and case reports on the use of cannabis by patients.
You may search for diseases (indications), authors, medication, study design (controlled study, open trial, case report etc.) and other criteria.




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TitleStriking lung cancer response to self-administration of cannabidiol: A case report and literature review.
Author(s)Sulé-Suso J, Watson NA, van Pittius DG, Jegannathen A.
Journal, Volume, IssueSAGE Open Med Case Rep. eCollection 2019.
Major outcome(s)CBD and a strong effect on a patient with lung cancer
IndicationCancerAbstract
MedicationCannabidiol

In spite of new drugs, lung cancer is associated with a very poor prognosis. While targeted therapies are improving outcomes, it is not uncommon for many patients to have only a partial response, and relapse during follow-up. Thus, new drugs or re-evaluation of existing therapies used to treat other non-malignant diseases (drug repurposing) are still needed. While this research both in vitro and in vivo is being carried out, it is important to be attentive to patients where the disease responds to treatments not considered standard in clinical practice. We report here a patient with adenocarcinoma of the lung who, after declining chemotherapy and radiotherapy, presented with tumour response following self-administration of cannabidiol, a non-psychoactive compound present in Cannabis sativa. Prior work has shown that cannabidiol may have anti-neoplastic properties and enhance the immune response to cancer. The data presented here indicate that cannabidiol might have led to a striking response in a patient with lung cancer.

Route(s)
Dose(s)
Duration (days)
Participants
DesignUncontrolled case report
Type of publicationMedical journal
Address of author(s)
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