On this site you will find clinical studies with cannabis or single
cannabinoids in different diseases and case reports on the use of cannabis by
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|Title||Combined THC and CBD to treat pain in epidermolysis bullosa: a report of three cases.|
|Author(s)||Schräder NHB, Duipmans JC, Molenbuur B, Wolff A, Jonkman MF.|
|Journal, Volume, Issue||Br J Dermatol. [Epub ahead of print]|
|Major outcome(s)||Cannabis effective against pain due to epidermolysis bullosa according to case reports|
Epidermolysis bullosa (EB) is a genetic blistering disorder characterized by intense pain related to disease pathology and care-based interventions. Opioid-based therapies underpin pain-care in EB however are unable to provide adequate analgesia in a significant proportion of patients. Cannabinoid-based medicines (CBMs) have been increasingly studied for pain conditions of various etiologies and pose as a novel dimension for pain-care in EB. We present three cases of EB who were prescribed pharmaceutical-grade sublingually administered CBMs comprising tetrahydrocannabinol (THC) and cannabidiol (CBD). All three patients reported improved pain scores, reduced pruritus and reduction in overall analgesic drug intake.
|Design||Uncontrolled case report|
|Type of publication||Medical journal|
|Address of author(s)|