On this site you will find clinical studies with cannabis or single
cannabinoids in different diseases and case reports on the use of cannabis by
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|Title||Pure delta-9-tetrahydrocannabinol and its combination with cannabidiol in treatment-resistant Tourette syndrome: A case report.|
|Author(s)||Pichler EM, Kawohl W, Seifritz E, Roser P.|
|Journal, Volume, Issue||Int J Psychiatry Med. [Epub ahead of print]|
|Major outcome(s)||A case report suggests that CBD may be beneficial in Tourette syndrome|
Objectives Anecdotal reports and preliminary studies suggest a therapeutic potential of cannabis in Tourette syndrome. We report the case of a female patient suffering from treatment-resistant Tourette syndrome. Methods Guideline-directed antipsychotic treatment with risperidone and aripiprazole as well as pure delta-9-tetrahydrocannabinol had no significant effect on Tourette syndrome symptomatology. Results Following administration of a daily dosage of 10 mg delta-9-tetrahydrocannabinol combined with 20 mg cannabidiol (CBD), the patient showed a rapid and highly significant improvement in the Yale Global Tic Severity Scale. Conclusions It can be speculated whether the beneficial effects may rely on the pharmacological properties of cannabidiol.
|Design||Uncontrolled case report|
|Type of publication||Medical journal|
|Address of author(s)|