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cannabinoids in different diseases and case reports on the use of cannabis by
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|Title||The use of cannabidiol for seizure management in patients with brain tumor-related epilepsy|
|Author(s)||Warren PP, Bebin EM, Nabors LB, Szaflarski JP|
|Journal, Volume, Issue||Neurocase. ;23(5-6):287-291|
|Major outcome(s)||CBD may be effective in epilepsy due to brain tumours according to a case series|
Epilepsy, commonly encountered by patients with brain tumors, is often refractory to standard therapies. Our aim was to examine the safety and efficacy of pharmaceutical grade cannabidiol (CBD; Epidiolex; Greenwich Biosciences) in those patients with epilepsy with concomitant tumors enrolled in The University of Alabama at Birmingham CBD Program (NCT02700412 and NCT02695537). Of the three patients with refractory seizures and a history of a primary brain tumor, two had improvement in seizure frequency and all three had improvement in seizure severity. These pilot results suggest that CBD should be further studied for the treatment of brain tumor-related epilepsy.
|Design||Uncontrolled case report|
|Type of publication||Medical journal|
|Address of author(s)|