On this site you will find clinical studies with cannabis or single
cannabinoids in different diseases and case reports on the use of cannabis by
You may search for diseases (indications), authors, medication, study design (controlled study, open trial, case report etc.) and other criteria.
|Title||An efficient new cannabinoid antiemetic in pediatric oncology.|
|Author(s)||Abrahamov A, Abrahamov A, Mechoulam R|
|Journal, Volume, Issue||Life Sciences 1995;56(23-24):2097-2102|
|Major outcome(s)||complete prevention of emesis|
|Indication||Cancer chemotherapy; Nausea/vomiting||Abstract|
Delta-8-tetrahydrocannabinol (delta-8-THC), a cannabinoid with lower psychotropic potency than the main Cannabis constituent, delta-9- tetrahydrocannabinol (delta-9-THC), was administered (18 mg/m2 in edible oil, p.o.) to eight children, aged 3-13 years with various hematologic cancers, treated with different antineoplastic drugs for up to 8 months. The total number of treatments with delta-8-THC so far is 480. The THC treatment started two hours before each antineoplastic treatment and was continued every 6 hrs for 24 hours. Vomiting was completely prevented. The side effects observed were negligible.
|Dose(s)||4 x 18 mg/m2 every 6 hours|
|Duration (days)||several days|
|Participants||8 children with cancer|
|Type of publication|
|Address of author(s)||Department of Pediatrics, Shaare Zedek Hospital, Jerusalem, Israel|