Clinical Studies and Case Reports

On this site you will find clinical studies with cannabis or single cannabinoids in different diseases and case reports on the use of cannabis by patients.
You may search for diseases (indications), authors, medication, study design (controlled study, open trial, case report etc.) and other criteria.

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TitleAn efficient new cannabinoid antiemetic in pediatric oncology.
Author(s)Abrahamov A, Abrahamov A, Mechoulam R
Journal, Volume, IssueLife Sciences 1995;56(23-24):2097-2102
Major outcome(s)complete prevention of emesis
IndicationCancer chemotherapy; Nausea/vomitingAbstract

Delta-8-tetrahydrocannabinol (delta-8-THC), a cannabinoid with lower psychotropic potency than the main Cannabis constituent, delta-9- tetrahydrocannabinol (delta-9-THC), was administered (18 mg/m2 in edible oil, p.o.) to eight children, aged 3-13 years with various hematologic cancers, treated with different antineoplastic drugs for up to 8 months. The total number of treatments with delta-8-THC so far is 480. The THC treatment started two hours before each antineoplastic treatment and was continued every 6 hrs for 24 hours. Vomiting was completely prevented. The side effects observed were negligible.

Dose(s)4 x 18 mg/m2 every 6 hours
Duration (days)several days
Participants8 children with cancer
DesignOpen study
Type of publication
Address of author(s)Department of Pediatrics, Shaare Zedek Hospital, Jerusalem, Israel
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