Clinical Studies and Case Reports

On this site you will find clinical studies with cannabis or single cannabinoids in different diseases and case reports on the use of cannabis by patients.
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TitleBeneficial Effect of Medical Cannabis in the Treatment of a Pharmacoresistant Nausea Associated with a Somatoform Disorder in a Patient with Post-Polio Syndrome
Author(s)Bleckwenn M, Weckbecker K, Voss S
Journal, Volume, IssueDtsch Med Wochenschr.;143(5):344-348
Major outcome(s)Cannabis improved nausea in a patient with post-polio syndrome
IndicationAbstract
MedicationCannabis

HISTORY AND CLINICAL FINDINGS:
 We report a 79-year-old patient with post-polio syndrome (PPS). In the course of this disease, recurrent upper abdominal pain and a therapy-resistant nausea developed without vomiting. In addition, the patient was limited by the combination of muscular weakness, obesity, dietary-treated diabetes and a degenerative spinal cord injury significantly in its mobility and physical capacity.

INVESTIGATIONS AND DIAGNOSIS:
 Despite extensive diagnostics, no somatic cause could be found neither for the nausea nor for the upper abdominal pain. Due to the psychological stress within the scope of the PPS, the development of a somatoform autonomic function disorder of the upper gastrointestinal tract may have occurred.

TREATMENT AND COURSE:
 Even under combination therapy of antiemetic and pain-modulating drugs, no adequate symptom control could be achieved. In the absence of therapy alternatives and increasing psychological strain the patient was prescribed medical cannabis. Under the therapy there was a relief of the nausea symptoms and decreased pain.

CONCLUSION:
 Cannabis is a treatment option for treatment-resistant symptoms as part of a PPS.

Route(s)
Dose(s)
Duration (days)
Participants
DesignUncontrolled case report
Type of publicationMedical journal
Address of author(s)
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