On this site you will find clinical studies with cannabis or single
cannabinoids in different diseases and case reports on the use of cannabis by
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|Title||Short-term effects of cannabinoids in patients with HIV-1 infection: a randomized, placebo-controlled clinical trial.|
|Author(s)||Abrams DI, Hilton JF, Leiser RJ, Shade SB, Elbeik TA, Aweeka FT, Benowitz NL, Bredt BM, Kosel B, Aberg JA, Deeks SG, Mitchell TF, Mulligan K, Bacchetti P, McCune JM, Schambelan M|
|Journal, Volume, Issue||Annals of Internal Medicine 2003;139(4):258-266|
|Major outcome(s)||Cannabis and THC had no significant effect on HI virus load and on CD4+ and CD8+ cell count|
Background: Cannabinoid use could potentially alter HIV RNA levels by two mechanisms: immune modulation or cannabinoid–protease inhibitor interactions (because both share cytochrome P-450 metabolic pathways).
|Dose(s)||3 x 2.5 mg THC; cannabis cigarette (3.95%THC) three times daily|
|Participants||67 patients with HIV-1 infection|
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