Clinical Studies and Case Reports

On this site you will find clinical studies with cannabis or single cannabinoids in different diseases and case reports on the use of cannabis by patients.
You may search for diseases (indications), authors, medication, study design (controlled study, open trial, case report etc.) and other criteria.




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TitleCannabis and other illicit drug use in epilepsy patients.
Author(s)Hamerle M, Ghaeni L, Kowski A, Weissinger F, Holtkamp M.
Journal, Volume, IssueEur J Neurol. 2014;21(1):167-70.
Major outcome(s)The use of cannabis did not affect disease severity in epilepsy.
IndicationEpilepsyAbstract
MedicationCannabis

BACKGROUND AND PURPOSE: This study aimed to assess the prevalence of illicit drug use among epilepsy patients and its effects on the disease.
METHODS: We systematically interviewed epilepsy outpatients at a tertiary epilepsy clinic. Predictors for active cannabis use were analysed with a logistic regression model.
RESULTS: Overall, 310 subjects were enrolled; 63 (20.3%) reported consuming cannabis after epilepsy was diagnosed, and 16 (5.2%) used other illicit drugs. Active cannabis use was predicted by sex (male) [odds ratio (OR) 5.342, 95% confidence interval (95% CI) 1.416-20.153] and age (OR 0.956, 95% CI 0.919-0.994). Cannabis consumption mostly did not affect epilepsy (84.1%). Seizure worsening was observed with frequent illicit (non-cannabis) drug use in 80% of cases.
CONCLUSIONS: Cannabis use does not seem to affect epilepsy; however, frequent use of other drugs increases seizure risk.

Route(s)Inhalation
Dose(s)
Duration (days)
Participants310 epilepsy patients
DesignSurvey
Type of publicationMedical journal
Address of author(s)Department of Neurology, Charité-University Hospital Berlin, Berlin, Germany.
Full textwww.ncbi.nlm.nih.gov/pubmed/23311572

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