On this site you will find clinical studies with cannabis or single
cannabinoids in different diseases and case reports on the use of cannabis by
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|Title||An open-label extension study to investigate the long-term safety and tolerability of THC/CBD oromucosal spray and oromucosal THC spray in patients with terminal cancer-related pain refractory to strong opioid analgesics|
|Author(s)||Johnson JR, Lossignol D, Burnell-Nugent M, Fallon MT|
|Journal, Volume, Issue||J Pain Symptom Manage. 2013 Aug;46(2):207-18|
|Major outcome(s)||The cannabis extract Sativex was generally well tolerated, with no evidence of a loss of effect for pain relief.|
CONTEXT: Chronic pain in patients with advanced cancer poses a serious clinical challenge. The Δ9-tetrahydrocannabinol (THC)/cannabidiol (CBD) oromucosal spray (U.S. Adopted Name, nabiximols; Sativex(®)) is a novel cannabinoid formulation currently undergoing investigation as an adjuvant therapy for this treatment group.
|Participants||43 patients with chronic cancer pain|
|Type of publication||Medical journal|
|Address of author(s)||Shropshire and Mid-Wales Hospice, Shrewsbury, Shropshire, United Kingdom|