Clinical Studies and Case Reports

On this site you will find clinical studies with cannabis or single cannabinoids in different diseases and case reports on the use of cannabis by patients.
You may search for diseases (indications), authors, medication, study design (controlled study, open trial, case report etc.) and other criteria.




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TitleCluster attacks responsive to recreational cannabis and dronabinol.
Author(s)Robbins MS, Tarshish S, Solomon S, Grosberg BM.
Journal, Volume, IssueHeadache. 2009 Jun;49(6):914-6.
Major outcome(s)Cannabis and THC aborted attacks of headaches.
IndicationHeadache/migraineAbstract
MedicationCannabis;Delta-9-THC

Pharmacological preparations of cannabinoid compounds have a variety of
therapeutic uses in medicine, including different pain syndromes, but have not
been previously reported as beneficial for cluster headache. We present a patient
with cluster headache who was refractory to multiple acute and preventive
medications but successfully aborted his attacks with recreational marijuana use;
subsequent use of dronabinol provided equally effective pain relief. The
beneficial effect may be related to the high concentration of cannabinoid
receptors in the hypothalamus, which has been implicated as a site of dysfunction
in neuroimaging studies of patients with cluster headache.

Route(s)Inhalation;Oral
Dose(s)
Duration (days)
Participants1 patient with cluster headaches
DesignUncontrolled case report
Type of publicationMedical journal
Address of author(s)Montefiore Headache Center, Saul R. Korey Department of Neurology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
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