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|Title||Comparison of bronchial effects of nabilone and terbutaline in healthy and asthmatic subjects.|
|Author(s)||Gong H Jr, Tashkin DP, Calvarese B|
|Journal, Volume, Issue||Journal of Clinical Pharmacology 1983;23(4):127-133|
|Major outcome(s)||moderate bronchodilator action in healthy subjects; no difference to placebo in asthmatics|
The acute bronchomotor effect of nabilone, a synthetic cannabinoid compound, was compared to that of terbutaline sulfate and placebo in six healthy and six asthmatic subjects. Bronchodilation following nabilone was intermediate between that of terbutaline and placebo in the healthy subjects but was equivalent to placebo in the asthmatics. We conclude that oral nabilone (2 mg) does not result in significant acute bronchodilation in patients with asthma.
|Participants||6 healthy subjects; 6 asthmatics|
|Type of publication|
|Address of author(s)|