Clinical Studies and Case Reports

On this site you will find clinical studies with cannabis or single cannabinoids in different diseases and case reports on the use of cannabis by patients.
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TitleCannabinoids improve driving ability in a Tourette's patient.
Author(s)Brunnauer A, Segmiller FM, Volkamer T, Laux G, Müller N, Dehning S
Journal, Volume, IssuePsychiatry Res. 2011 Dec 30;190(2-3):382.
Major outcome(s)THC improved driving ability
IndicationTourette's syndromeAbstract
MedicationDelta-9-THC

No abstract available.

Summary:

Physicians at the Ludwig-Maximilians University in Munich and the Inn-Salzach Hospital, Germany, presented the case of a 42-year-old truck driver with Tourette syndrome since the age of 6. He exhibited multiple tics and repeatedly standing up and down. Mostly, he was suffering from obsessive thoughts. All standard medications for tic disorders had proven ineffective. After two weeks of a treatment with increasing doses of THC (up to 15 mg a day) tics were significantly reduced.

Since the patient required daily driving his driving ability was assessed with computerized tests, according to the German guidelines for road and traffic safety. Both in the drug-free phase and during THC therapy, the criteria according to German regulations were met in all functional domains investigated (visual perception, capacity of reaction, concentration and stress-tolerance). In comparison with the drug-free phase, there was a clear improvement in concentration and visual perception during the treatment with THC.

Route(s)Oral
Dose(s)15 mg
Duration (days)14
Participants1 patient with Tourette's syndrome
DesignUncontrolled case report
Type of publicationMedical journal
Address of author(s)Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-University, Munich, Germany; Psychiatric Clinic, Inn-Salzach Hospital Wasserburg/Inn, Germany.
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