Clinical Studies and Case Reports

On this site you will find clinical studies with cannabis or single cannabinoids in different diseases and case reports on the use of cannabis by patients.
You may search for diseases (indications), authors, medication, study design (controlled study, open trial, case report etc.) and other criteria.




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TitleNabilone for the treatment of paraneoplastic night sweats: a report of four cases.
Author(s)Maida V.
Journal, Volume, IssueJ Palliat Med. 2008 Jul;11(6):929-34.
Major outcome(s)Significant improvement of night sweats within 2 days
IndicationCancerAbstract
MedicationNabilone

ABSTRACT Night sweats are one of many symptoms experienced by patients with advanced cancer. The prevalence of night sweats ranges from 10%-48% in cancer patients. Persistent night sweats tend to decrease quality of life through interference with sleep. A recent study has demonstrated that night sweats occur as part of a symptom pattern, and are associated with the anorexia-cachexia symptom cluster. In addition, night sweats represent one of the symptoms that displays a tendency not to improve as patients with advanced cancer approach end of life. This paper serves to report on the successful management of four patients suffering from persistent paraneoplastic night sweats using the synthetic orally administered cannabinoid nabilone. The four patients had been referred to a regional consultative palliative medicine program and identified night sweats as one of their most significant symptomatic concerns reported on their Edmonton Symptom Assessment System (ESAS) questionnaires.

Route(s)Oral
Dose(s)1 - 2 x 1 mg
Duration (days)14
Participants4 advanced cancer patients with severe night sweats
DesignOpen study
Type of publicationMedical journal
Address of author(s)Division of Palliative Medicine, William Osler Health Centre, University of Toronto, Toronto, Canada. vincent.maida@utoronto.ca
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