Clinical Studies and Case Reports

On this site you will find clinical studies with cannabis or single cannabinoids in different diseases and case reports on the use of cannabis by patients.
You may search for diseases (indications), authors, medication, study design (controlled study, open trial, case report etc.) and other criteria.




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TitleAn initial evaluation of Nabilone in the control of radiotherapy-induced nausea and vomiting.
Author(s)Priestman TJ, Priestman SG.
Journal, Volume, IssueClin Radiol. 1984 Jul;35(4):265-6.
Major outcome(s)Patients who did not respond to metaclopramide responded to nabilone.
IndicationNausea/vomiting;CancerAbstract
MedicationNabilone

Nabilone is a cannabinoid anti-emetic which has been extensively evaluated in control of chemotherapy-induced vomiting. A pilot study was undertaken to assess the efficacy of Nabilone in controlling radiotherapy-induced vomiting resistant to a conventional anti-emetic (metoclopramide). Thirty patients receiving wide-field upper abdominal irradiation were prospectively monitored. Fourteen developed no significant nausea or vomiting and in 10 symptoms were controlled by metaclopramide. All six patients who failed to respond to this agent responded to Nabilone. Toxicity with both drugs was minimal. Although patient numbers were small, this initial assessment suggests that Nabilone may be a useful agent in the control of resistant radiation-induced sickness.

Route(s)Oral
Dose(s)
Duration (days)
Participants30 patients undergoing radiotherapy
DesignOpen study
Type of publicationMedical journal
Address of author(s)
Full text

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