On this site you will find clinical studies with cannabis or single
cannabinoids in different diseases and case reports on the use of cannabis by
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|Title||The efficacy and safety of nabilone (a synthetic cannabinoid) in the treatment of anxiety.|
|Author(s)||Fabre LF, McLendon D.|
|Journal, Volume, Issue||J Clin Pharmacol. 1981 Aug-Sep;21(8-9 Suppl):377S-382S.|
|Major outcome(s)||Dramatic improvement in anxiety|
The ANXIOLYTIC properties of nabilone, a synthetic cannabinoid resembling the natural cannabinoids, were studied in 25 outpatients suffering from anxiety. The drug was compared with a placebo in a double-blind manner over a 28-day treatment period. Patients were seen weekly by the physician and were rated by the Hamilton Rating Scale for Anxiety and the Patient's Global Evaluation as well as by patient-rated evaluations. The results of the study showed a dramatic improvement in anxiety in the nabilone group when compared with placebo (P less than 0.001). Side effects reported were dry mouth, dry eyes, and drowsiness. Patients did not report any of the subjective "altered state" experience of marihuana.
|Participants||25 patients with anxiety|
|Type of publication||Medical journal|
|Address of author(s)|