On this site you will find clinical studies with cannabis or single
cannabinoids in different diseases and case reports on the use of cannabis by
patients.
You may search for diseases (indications), authors, medication,
study design (controlled study, open trial, case report etc.) and other criteria.
If you want to add a study or a case report please click
here. Studies and case reports will be checked by the IACM before publication in this database. Please do not forget to enter your e-mail address in the field "address of author" for any request.
| Title | Analgesic effect of the cannabinoid analogue nabilone is not mediated by opioid receptors. |
|---|
| Author(s) | Hamann W, di Vadi PP. |
|---|
| Journal, Volume, Issue | Lancet 1999;353(9152):560. |
|---|
| Major outcome(s) | Relieve of pain |
|---|
|
| Indication | Multiple sclerosis;Pain | Abstract |
|---|
| Medication | Nabilone | (no abstract available)
Excerpt from the case report:
"(...) The patient had been suffering with severe and intractable pain in both legs caused by multiple sclerosis. The pain was eventually relieved by a low daily dose of nabilone (1 mg twice a day), after a large variety of unsuccessful trials with antineuropathic and antinociceptive treatments. (...) The VAS (initial value: 8) started to decrease 10 min after oral nabilone was taken and dropped to 0 (no pain) after 120 min; it remained unchanged for an additional 120 min and then started to return. At the time the patient left (260 min after oral nabilone intake), the pain was still reduced (VAS: 5). (...)." |
|---|
| Route(s) | Oral |
|---|
| Dose(s) | 2 x 1mg |
|---|
| Duration (days) | 1 |
|---|
| Participants | 1 patient with multiple sclerosis and pain |
|---|
| Design | Open study |
|---|
| Type of publication | Medical journal |
|---|
| Address of author(s) | Pain Management Unit, Department of Anaesthetics, Guy's Hospital, London, UK |
|---|
| Full text |
 |
|---|
