Clinical Studies and Case Reports

On this site you will find clinical studies with cannabis or single cannabinoids in different diseases and case reports on the use of cannabis by patients.
You may search for diseases (indications), authors, medication, study design (controlled study, open trial, case report etc.) and other criteria.




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TitleAnalgesic effect of the cannabinoid analogue nabilone is not mediated by opioid receptors.
Author(s)Hamann W, di Vadi PP.
Journal, Volume, IssueLancet 1999;353(9152):560.
Major outcome(s)Relieve of pain
IndicationMultiple sclerosis;PainAbstract
MedicationNabilone

(no abstract available)
Excerpt from the case report:
"(...) The patient had been suffering with severe and intractable pain in both legs caused by multiple sclerosis. The pain was eventually relieved by a low daily dose of nabilone (1 mg twice a day), after a large variety of unsuccessful trials with antineuropathic and antinociceptive treatments. (...) The VAS (initial value: 8) started to decrease 10 min after oral nabilone was taken and dropped to 0 (no pain) after 120 min; it remained unchanged for an additional 120 min and then started to return. At the time the patient left (260 min after oral nabilone intake), the pain was still reduced (VAS: 5). (...)."

Route(s)Oral
Dose(s)2 x 1mg
Duration (days)1
Participants1 patient with multiple sclerosis and pain
DesignOpen study
Type of publicationMedical journal
Address of author(s)Pain Management Unit, Department of Anaesthetics, Guy's Hospital, London, UK
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