Clinical Studies and Case Reports

On this site you will find clinical studies with cannabis or single cannabinoids in different diseases and case reports on the use of cannabis by patients.
You may search for diseases (indications), authors, medication, study design (controlled study, open trial, case report etc.) and other criteria.

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TitleEffect of cannabinoids on spasticity and ataxia in multiple sclerosis.
Author(s)Meinck HM, Schönle PW, Conrad B
Journal, Volume, IssueJournal of Neurology 1989;236(2):120-122
Major outcome(s)improvement of tremor, spasticity and ataxia
IndicationMultiple sclerosis; Spasticity; AtaxiaAbstract

The chronic motor handicaps of a 30-year-old multiple sclerosis patient acutely improved while he smoked a marihuana cigarette. This effect was quantitatively assessed by means of clinical rating, electromyographic investigation of the leg flexor reflexes and electromagnetic recording of the hand action tremor. It is concluded that cannabinoids may have powerful beneficial effects on both spasticity and ataxia that warrant further evaluation.

Dose(s)1 cannabis cigarette of unknown THC content
Duration (days)1
Participants1 patient with multiple sclerosis
DesignControlled study
Type of publication
Address of author(s)Department of Clinical Neurophysiology, University of Göttingen, Germany
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