Clinical Studies and Case Reports

On this site you will find clinical studies with cannabis or single cannabinoids in different diseases and case reports on the use of cannabis by patients.
You may search for diseases (indications), authors, medication, study design (controlled study, open trial, case report etc.) and other criteria.




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TitleThe analgesic properties of delta-9-tetrahydrocannabinol and codeine.
Author(s)Noyes R Jr, Brunk SF, Avery DAH, Canter AC
Journal, Volume, IssueClinical Pharmacology and Therapeutics 1975;18(1):84-89
Major outcome(s)milde analgesic effect; with 20 mg THC strong adverse effects
IndicationCancer; PainAbstract
MedicationDelta-9-THC

The administration of single oral doses of delta-9- tetrahydrocannabinol (THC) to patients with cancer pain demonstrated a mild analgesic effect. At a dose of 20 mg, however, THC induced side effects that would prohibit its therapeutic use including somnolence, dizziness, ataxia, and blurred vision. Alarming adverse reactions were also observed at this dose. THC, 10 mg, was well tolerated and, despite its sedative effect, may analgesic potential.

Route(s)Oral
Dose(s)10-20 mg
Duration (days)
Participants36 cancer patients
DesignControlled study
Type of publication
Address of author(s)
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