Clinical Studies and Case Reports

On this site you will find clinical studies with cannabis or single cannabinoids in different diseases and case reports on the use of cannabis by patients.
You may search for diseases (indications), authors, medication, study design (controlled study, open trial, case report etc.) and other criteria.




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Title[Fitness to drive in spite (because) of THC] [Article in German]
Author(s)Strohbeck-Kühner P, Skopp G, Mattern R.
Journal, Volume, IssueArch Kriminol. 2007;220(1-2):11-9.
Major outcome(s)Significant improvement of driving-related performance
IndicationAbstract
MedicationCannabis

Attention-deficit/hyperactivity disorder (ADHD) is characterized by a lack of concentration and/or an altered activation level. People with ADHD are found to violate traffic regulations, to commit criminal offences and to be involved in traffic accidents more often than the statistical norm. Furthermore, they show more deviant behaviour and have an increased co-morbidity regarding substance abuse and dependence. Hence, this disorder is of some forensic importance. The purpose of this case study is to demonstrate that in some cases people with ADHD may show unusual effects after the consumption of THC. A 28-year-old male, who showed abnormal behaviour and seemed to be significantly maladjusted and inattentive while sober, appeared to be completely normal with a very high plasma level of THC. Performance tests conducted with the test batteries ART2020 and TAP provided average and partly above-average results in functions related to driving. Thus, it has to be taken into account that in persons with ADHD THC may have atypical and even performance-enhancing effects.

Route(s)Inhalation
Dose(s)1 cannabis cigarette
Duration (days)1
Participants1 patient with attention-deficit/hyperactivity disorder (ADH
DesignUncontrolled case report
Type of publicationMedical journal
Address of author(s)Institut für Rechtsmedizin und Verkehrsmedizin der Universität Heidelberg, Germany
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