Clinical Studies and Case Reports

On this site you will find clinical studies with cannabis or single cannabinoids in different diseases and case reports on the use of cannabis by patients.
You may search for diseases (indications), authors, medication, study design (controlled study, open trial, case report etc.) and other criteria.




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TitleAnalgesic effect of delta-9-tetrahydrocannabinol.
Author(s)Noyes R Jr, Brunk SF, Baram DA, Canter A
Journal, Volume, IssueJournal of Clinical Pharmacology 1975;15(2-3):139-143
Major outcome(s)pain relief with 15-20 mg THC
IndicationCancer; PainAbstract
MedicationDelta-9-THC

A preliminary trial of oral delta-9-tetrahydrocannabinol (THC) demonstrated an analgesic effect of the drug in patients experiencing cancer pain. Placebo and 5, 10, 15, and 20 mg THC were administered double blind to ten patients. Pain relief significantly superior to placebo was demonstrated at high dose levels (15 and 20 mg). At these levels, substantial sedation and mental clouding were reported.

Route(s)Oral
Dose(s)5-20 mg
Duration (days)
Participants10 cancer patients
DesignControlled study
Type of publication
Address of author(s)
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