On this site you will find clinical studies with cannabis or single
cannabinoids in different diseases and case reports on the use of cannabis by
You may search for diseases (indications), authors, medication, study design (controlled study, open trial, case report etc.) and other criteria.
|Title||The effect of delta-9-THC on human spasticity.|
|Author(s)||Hanigan WC, Destree R, Truong XT.|
|Journal, Volume, Issue||Clinical Pharmacology and Therapeutics 1986;39:198.|
|Major outcome(s)||Delta-9-THC proved clinically beneficial in two of five patients with intractable spasticity.|
Five patients with traumatic paraplegia were given oral Delta-9-THC at 35 mg/day in a double blind, 20-day crossover trial. Separate investigators graded muscle resistance and deep tendon reflexes while patients and nursing staff evaluated spasticity using a visual analog scale. Mean scores for each trial period were compared using unpaired t-tests.
|Participants||5 patients with traumatic paraplegia|
|Type of publication||Medical journal|
|Address of author(s)|