Clinical Studies and Case Reports

On this site you will find clinical studies with cannabis or single cannabinoids in different diseases and case reports on the use of cannabis by patients.
You may search for diseases (indications), authors, medication, study design (controlled study, open trial, case report etc.) and other criteria.




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TitleEffect of a nitrogen analog of tetrahydrocannabinol on cancer pain.
Author(s)Staquet M, Gantt C, Machin D.
Journal, Volume, IssueClin Pharmacol Ther. 1978 Apr;23(4):397-401.
Major outcome(s)NIB was superior to placebo and to secobarbital but is not useful clinically because of the frequency of side effects.
IndicationCancer;PainAbstract
MedicationOther cannabinoids

Two consecutive, randomized, double-blind trials were performed to test the analgesic properties of a synthetic nitrogen analog of tetrahydrocannabinol (NIB). In the first trial, the test preparation was superior to placebo and approximately equivalent to 50 mg of codeine phosphate. In the second study, the tetrahydrocannabinol analog was superior to placebo and to 50 mg secobarbital. NIB is not useful clinically because of the frequency of side effects.

Route(s)
Dose(s)4 mg
Duration (days)
Participants45 cancer patients
DesignControlled study
Type of publicationMedical journal
Address of author(s)
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