Clinical Studies and Case Reports

On this site you will find clinical studies with cannabis or single cannabinoids in different diseases and case reports on the use of cannabis by patients.
You may search for diseases (indications), authors, medication, study design (controlled study, open trial, case report etc.) and other criteria.




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TitleRandomised clinical trial of levonantradol and chlorpromazine in the prevention of radiotherapy-induced vomiting.
Author(s)Lucraft HH, Palmer MK
Journal, Volume, IssueClinical Radiology. 1982 Nov;33(6):621-2.
Major outcome(s)The frequency of vomiting was similar after levonantradol and chlorpromazine.
IndicationNausea/vomitingAbstract
MedicationOther cannabinoids

Levonantradol is a cannabis derivative. Cannabinoid anti-emetics are being assessed in cancer chemotherapy but have been little used in radiotherapy to date. A pilot study and randomised trial compared the anti-emetic effect of a standard drug (Chlorpromazine 26 mg) with Levonantradol at two doses (0.5 and 0.75 mg) in patients receiving palliative single fraction radiotherapy to sites likely to cause nausea and vomiting. Most patients were out-patients. Both drugs were well tolerated. The frequency of vomiting was similar in all three groups in both the pilot study and randomised trial.

Route(s)
Dose(s)0.5-0.75 mg
Duration (days)
ParticipantsPatients undergoing radiotherapy
DesignControlled study
Type of publicationMedical journal
Address of author(s)
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