Clinical Studies and Case Reports

On this site you will find clinical studies with cannabis or single cannabinoids in different diseases and case reports on the use of cannabis by patients.
You may search for diseases (indications), authors, medication, study design (controlled study, open trial, case report etc.) and other criteria.




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TitleThe perceived effects of smoked cannabis on patients with multiple sclerosis.
Author(s)Consroe P, Musty R, Rein J, Tillery W, Pertwee R
Journal, Volume, IssueEuropean Neurology 1997;38(1):44-48
Major outcome(s)In more than 80% improvement of spasticity, pain, tremor, depression, anxiety, and paresthesia
IndicationSpasticity;Multiple sclerosis;Pain;Tremor;DepressionAbstract
MedicationCannabis

Fifty-three UK and 59 USA people with multiple sclerosis (MS) answered anonymously the first questionnaire on cannabis use and MS. From 97 to 30% of the subjects reported cannabis improved (in descending rank order): spasticity, chronic pain of extremities, acute paroxysmal phenomenon, tremor, emotional dysfunction, anorexia/weight loss, fatigue states, double vision, sexual dysfunction, bowel and bladder dysfunctions, vision dimness, dysfunctions of walking and balance, and memory loss. The MS subjects surveyed have specific therapeutic reasons for smoking cannabis. The survey findings will aid in the design of a clinical trial of cannabis or cannabinoid administration to MS patients or to other patients with similar signs or symptoms.

Route(s)Inhalation;Oral
Dose(s)variable
Duration (days)months to years
Participants112 patients with multiple sclerosis
DesignSurvey
Type of publication
Address of author(s)Department of Pharmacology/Toxicology, University of Arizona Health Sciences Center, Tucson, USA
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