On this site you will find clinical studies with cannabis or single
cannabinoids in different diseases and case reports on the use of cannabis by
patients.
You may search for diseases (indications), authors, medication,
study design (controlled study, open trial, case report etc.) and other criteria.
| Title | Nabilone and metoclopramide in the treatment of nausea and vomiting due to cisplatinum: a double blind study. |
|---|
| Author(s) | Crawford SM, Buckman R. |
|---|
| Journal, Volume, Issue | Med Oncol Tumor Pharmacother. 1986;3(1):39-42. |
|---|
| Major outcome(s) | No difference between nabilone and metoclopramide |
|---|
|
| Indication | Nausea/vomiting;Cancer;Cancer chemotherapy | Abstract |
|---|
| Medication | Nabilone | Thirty-two patients were entered into a double blind trial of antiemetic support in patients being treated with cisplatin. Patients were allocated to receive either oral nabilone (1 mg 8 hourly) or intravenous metoclopramide (1 mg kg-1 3 hourly) in random order over 4 courses. There was no difference between the two treatments in the overall incidence or severity of vomiting, although a subgroup of patients enjoyed a substantial reduction in episodes of vomiting whilst receiving metoclopramide. Side-effects were predictable from the pharmacology of the drugs. |
|---|
| Route(s) | Oral |
|---|
| Dose(s) | 1 mg 8 hourly |
|---|
| Duration (days) | |
|---|
| Participants | 32 patients treated with cisplatin |
|---|
| Design | Controlled study |
|---|
| Type of publication | Medical journal |
|---|
| Address of author(s) | Department of Medical Oncology, Charing Cross Hospital, London W6 8RF; Department of Oncology, University College Hospital, London WC1, U.K. |
|---|
| Full text |
 |
|---|
