Clinical Studies and Case Reports

On this site you will find clinical studies with cannabis or single cannabinoids in different diseases and case reports on the use of cannabis by patients.
You may search for diseases (indications), authors, medication, study design (controlled study, open trial, case report etc.) and other criteria.




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TitleBehavioral analysis of marijuana effects on food intake in humans.
Author(s)Foltin RW, Fishman MW, Brady JV.
Journal, Volume, IssuePharmacology, Biochemistry and Behavior 1986;25:577-582.
Major outcome(s)The administration of two or three active marijuana cigarettes during the social access period increased average daily caloric intake.
IndicationAppetite loss/weight lossAbstract
MedicationCannabis

Nine male research volunteers, in three groups of three subjects each, resided in a residential laboratory for up to 25 days. All contact with the experimenter was through a networked computer system and subjects’ behaviors including food intake were continuously recorded. Subjects brought their own activities such as model-making, and these in combination with those provided by the laboratory resulted in rich behavior repertoires. During the first part of the day, subjects remained in their private rooms doing planned work activities, and during the remainder of the day, they were allowed to socialize. Cigarettes containing active marijuana (1.84% THC) or placebo were smoked prior to the private work period and during the social access period. A single active marijuana cigarette prior to the private work period had no effect on food intake. The administration of two or three active marijuana cigarettes during the social access period increased average daily caloric intake. The increased intake was due to an augmentation of calories consumed as between-meal snack items rather than an increase in meal size per se.

Route(s)Inhalation
Dose(s)
Duration (days)up to 25
ParticipantsNine male research volunteers
DesignControlled study
Type of publicationMedical journal
Address of author(s)
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