On this site you will find clinical studies with cannabis or single
cannabinoids in different diseases and case reports on the use of cannabis by
patients.
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| Title | Amelioration of cancer chemotherapy-induced nausea and vomiting by delta-9-tetrahydrocannabinol. |
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| Author(s) | Ekert H, Waters KD, Jurk IH, Mobilia J, Loughnan P |
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| Journal, Volume, Issue | Med J Aust. 1979 Dec 15;2(12):657-9. |
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| Major outcome(s) | THC was effective in reducing nausea and vomiting but not in all patients |
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| Indication | Nausea/vomiting | Abstract |
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| Medication | Delta-9-THC | The antinausea and antivomiting effects of delta-9-tetrahydrocannabinol (THC) in children receiving cancer chemotherapy were compared with those of metoclopramide syrup and prochlorperazine tablets in two double-blind studies. THC was found to be a significantly better antinausea and antivomiting agent, but not all patients obtained relief of nausea and vomiting with THC. In some patients, THC enhanced appetite during a course of chemotherapy. In two patients, a "high" associated with THC administrationwas reported. Drowsiness was reported significantly more frequently with THC. |
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| Route(s) | Oral |
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| Dose(s) | 10 mg/m2 2 hr prior to chemo and 4, 8, 16 and 24 h after the first dose; |
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| Duration (days) | |
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| Participants | Children receiving cancer chemotherapy |
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| Design | Controlled study |
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| Type of publication | Medical journal |
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| Address of author(s) | |
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