Clinical Studies and Case Reports

On this site you will find clinical studies with cannabis or single cannabinoids in different diseases and case reports on the use of cannabis by patients.
You may search for diseases (indications), authors, medication, study design (controlled study, open trial, case report etc.) and other criteria.




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TitleAmelioration of cancer chemotherapy-induced nausea and vomiting by delta-9-tetrahydrocannabinol.
Author(s)Ekert H, Waters KD, Jurk IH, Mobilia J, Loughnan P
Journal, Volume, IssueMed J Aust. 1979 Dec 15;2(12):657-9.
Major outcome(s)THC was effective in reducing nausea and vomiting but not in all patients
IndicationNausea/vomitingAbstract
MedicationDelta-9-THC

The antinausea and antivomiting effects of delta-9-tetrahydrocannabinol (THC) in children receiving cancer chemotherapy were compared with those of metoclopramide syrup and prochlorperazine tablets in two double-blind studies. THC was found to be a significantly better antinausea and antivomiting agent, but not all patients obtained relief of nausea and vomiting with THC. In some patients, THC enhanced appetite during a course of chemotherapy. In two patients, a "high" associated with THC administrationwas reported. Drowsiness was reported significantly more frequently with THC.

Route(s)Oral
Dose(s) 10 mg/m2 2 hr prior to chemo and 4, 8, 16 and 24 h after the first dose;
Duration (days)
ParticipantsChildren receiving cancer chemotherapy
DesignControlled study
Type of publicationMedical journal
Address of author(s)
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