On this site you will find clinical studies with cannabis or single
cannabinoids in different diseases and case reports on the use of cannabis by
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|Title||Amelioration of cancer chemotherapy-induced nausea and vomiting by delta-9-tetrahydrocannabinol.|
|Author(s)||Ekert H, Waters KD, Jurk IH, Mobilia J, Loughnan P|
|Journal, Volume, Issue||Med J Aust. 1979 Dec 15;2(12):657-9.|
|Major outcome(s)||THC was effective in reducing nausea and vomiting but not in all patients|
The antinausea and antivomiting effects of delta-9-tetrahydrocannabinol (THC) in children receiving cancer chemotherapy were compared with those of metoclopramide syrup and prochlorperazine tablets in two double-blind studies. THC was found to be a significantly better antinausea and antivomiting agent, but not all patients obtained relief of nausea and vomiting with THC. In some patients, THC enhanced appetite during a course of chemotherapy. In two patients, a "high" associated with THC administrationwas reported. Drowsiness was reported significantly more frequently with THC.
|Dose(s)||10 mg/m2 2 hr prior to chemo and 4, 8, 16 and 24 h after the first dose;|
|Participants||Children receiving cancer chemotherapy|
|Type of publication||Medical journal|
|Address of author(s)|