On this site you will find clinical studies with cannabis or single
cannabinoids in different diseases and case reports on the use of cannabis by
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|Title||Delta-9-tetrahydrocannabinol shows antispastic and analgesic effects in a single case double-blind trial.|
|Author(s)||Maurer M, Henn V, Dittrich A, Hofmann A|
|Journal, Volume, Issue||Eur Arch Psychiatry Clin Neurosci 1990;240(1):1-4|
|Major outcome(s)||THC and codeine reduced pain; THC reduced spasticity|
|Indication||Spasticity;Spinal cord injury;Pain||Abstract|
A double-blind study was performed comparing 5 mg delta-9- tetrahydrocannabinol (THC) p.o., 50 mg codeine p.o., and placebo in a patient with spasticity and pain due to spinal cord injury. The three conditions were applied 18 times each in a randomized and balanced order. Delta-9-THC and codeine both had an analgesic effect in comparison with placebo. Only delta-9-THC showed a significant beneficial effect on spasticity. In the dosage of THC used no altered consciousness occurred.
|Dose(s)||5 mg per day|
|Participants||1 patient with spinal cord injury|
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|Address of author(s)|