Studies
en Gevallenrapporten
Laatste update: 15 juni 2008
U vindt wetenschappelijke informatie over
talrijke studies in de Database on Clinical Studies and
Case Reports
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Verbetering van de symptomen of positieve evaluatie door de auteurs
o
Geen relevante verandering in de symptomen of negatieve evaluatie door de
auteurs
v Verslechtering van de
symptomen
Misselijkheid en
Braken – Kanker Chemotherapie
Gecontroleerde
Studies
Dronabinol
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Artim R, DiBella N. Tetrahydrocannabinol (THC) plus prochlorperazine (PCZ)
for refractory nausea and vomiting (N/V). Proceedings of the American Society
for Clinical Oncology 1983;2:84.
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Chang AE, Shiling DJ, Stillman RC, Goldberg NH, Seipp CA, Barofsky I.
Delta-9-tetrahydrocannabinol as an antiemetics in cancer patients receiving
high-dose methotrexate. Annals of Internal Medicine 1979;91:819-824.
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Chang AE, Shiling DJ, Stillman RC, Goldberg NH, Seipp CA, Barofsky I, Rosenberg
SA.. A prospective evaluation of delta-9-tetrahydrocannabinol as an antiemetic
in patients receiving adriamycin and cytoxan chemotherapy. Cancer 1981; 47:
1746-1751.
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Colls BM, Ferry DG, Gray AJ, Harvey VJ, McQueen EG. The antiemetic activity
of tetrahydrocanabinol versus metoclopramide and thiethylperazine in patients
undergoing cancer chemotherapy. New Zealand Medical Journal 1980;91:449-451.
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Ekert H, Waters KD, Jurk KH, Mobilia J, Loughnan P. Ameriloration of cancer
chemotherapy-induced nausea and vomiting by delta-9-tetrahydrocannabinol.
Medical Journal of Australia 1979;2:657-659.
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Frytak S, Moertel CG, O'Fallon JR, Rubin J, Creagan ET, O'Connnell MJ.
Delta-9-tetrahydrocannabinol as an antiemetics for patients receiving cancer
chemotherapy. A comparison with prochlorperazine and a placebo. Annals of
Internal Medicine 1979;91:825-830.
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Gralla RJ, Tyson LB, Bordin LA, Clark RA, Kelsen DP, Kris MG. Antiemetic
therapy: a review of recent studies and a report of a random assignment trial
comparing metoclopramide with delta-9-tetrahydrocannabinol. Cancer Treatment
Report 1984;68:163-172.
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Kluin-Nelemans JC, Nelemans FA, Meuwissen OJATh, Maes RAA. D9-tetrahydrocannabinol (THC) as an
antiemetic in patients treated with cancer chemotherapy; a double-blind cross-over
trial against placebo. Veterinary and Human Toxicology 1979;21:338-340.
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Lane M, Vogel CL, Ferguson J, Krasnow S, Saiers JL, Hamm J. Dronabinol and
prochlorperazine in combination for treatment of cancer chemotherapy-induced
nausea and vomiting. Journal of Pain and Symptom Management 1991;6:352-359.
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Levitt M, Faiman C, Hawks R, Wilson A. Randomized double blind comparison
of delta-9-tetrahydroicannabinol (THC) and marijuana as chemotherapy
antiemetics. Proceedings of the American Society for Clinical Oncology
1984;3:91.
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Levitt M, Wilson A, Bowman D, Faiman C, Kemel S, Krepart G. Dose vs
response of tetrahydroannabinol (THC) vs prochlorperazine as chemotherapy
antiemetics. Proceedings of the American Society for Clinical Oncology
1981;22:422.
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McCabe M, Smith FP, Goldberg D, Macdonald J, Woolley PV, Warren R. Efficacy
of tetrahydrocannabinol in patients refractory to standard anti-emetic therapy.
Investigational New Drugs 1988;6:243-246.
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Neidhart JA, Gagen MM, Wilson HE, Young DC. Comparative trial of the
antiemetic effects of THC and haloperidol. International Journal of Clinical
Pharmacology Research 1981; 21: 38-42S.
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Orr LE, McKernan JF, Bloome B. Antiemetic effect of tetrahydrocannabinol.
Compared with placebo and prochlorperazine in chemotherapy-associated nausea
and emesis. Archives of Internal Medicine 1980;140:1431-433.
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Sallan SE, Cronin C, Zelen M, Zinberg NE. Antiemetics in patients receiving
chemotherapy for cancer. A randomized comparison of
delta-9-tetrahydrocannabinol and prochlorperazine. New England Journal of
Medicine 1980;302:135-138.
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Sallan SE, Zinberg NE, Frei E. Antiemetic effect of
delta-9-tetrahydrocannabinol in patients receiving cancer chemotherapy. New
England Journal of Medicine 1975;293:795-797.
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Ungerleider JT, Andrysiak T, Fairbanks L, Goodnight J, Sarna G, Jamison K.
Cannabis and cancer chemotherapy. A comparison of oral delta-9-THC and
prochlorperazine. Cancer 1982;50:636-645.
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Ungerleider JT, Sarna G, Fairbanks LA, Goodnight J, Andrysiak T, Jamison K.
THC or compazine for the cancer chemotherapy patient
the
UCLA study. Part II: patient drug preference. American Journal of Clinical
Oncology 1985; 8: 142-147.
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Meiri E, Jhangiani H, Vredenburgh JJ, Barbato LM, Carter FJ, Yang HM,
Baranowski V. Efficacy of dronabinol alone and in combination with ondansetron
versus ondansetron alone for delayed chemotherapy-induced nausea and vomiting.
Curr Med Res Opin 2007;23(3):533-43.
Cannabis (gerookt)
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Levitt M, Faiman C, Hawks R, Wilson A. Randomized double blind comparison
of delta-9-tetrahydroicannabinol (THC) and marijuana as chemotherapy
antiemetics. Proceedings of the American Society for Clinical Oncology
1984;3:91.
Nabilone
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Ahmedzai S, Carlyle DL, Clader IT, Moran F. Anti-emetic efficacy and
toxicity of nabilone, a synthetic cannabinoid, in lung cancer chemotherapy.
British Journal of Cancer 1983;48:657-663.
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Chan HS, Correia JA, MacLeod SM. Nabilone versus prochlorperazine for
control of cancer chemotherapy-induced emesis in children: a double-blind,
crossover trial. Pediatrics 1987; 79: 946-952
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Crawford SM, Buckman R. Nabilone and metoclopramide in the treatment of
nausea and vomiting due to cisplatinum: a double blind study. Medical Oncology
and Tumor Pharmacotherapy 1986; 3: 39-42.
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Cunningham D, Bradley CJ, Forrest GJ, Hutcheon AW, Adams L, Sneddon M, et
al. A randomized trial of oral nabilone and prochlorperazine compared to
intravenous metoclopramide and dexamethasone in the treatment of nausea and vomiting
induced by chemotherapy regimens containing cisplatin or cisplatin analogues.
European Journal of Cancer and Clinical Oncology 1988; 24: 685-689.
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